K means clustering

K means

Complete dataset

Joining everything:

K-means clustering with 9 clusters of sizes 29, 52, 1, 112, 22, 241, 133, 5, 9

Cluster means:
     sum_AGEs  sum_acetyl    sum_Kacyl   sum_oxPTMs sum_phospho    sum_ubiq
1  3.37868720  0.03220139  1.717553047  1.218420232  -0.2008470  0.27987039
2  0.09739856 -0.08993029 -0.008535214 -0.007444554  -0.2069497 -0.06560473
3 -0.06111326  0.15343671 13.754972675 12.023702972   6.6491871  0.94645574
4 -0.34827300 -0.14127678 -0.165647056 -0.383558084   0.4599978 -0.24193913
5 -0.21077431 -0.13146019 -0.015714009 -0.058546079  -0.0547253 -0.07225921
6 -0.14607754 -0.05382450 -0.170146326 -0.018117898  -0.2198687 -0.04674529
7 -0.17047409 -0.11484986 -0.157641666 -0.116325441  -0.1791270 -0.12060570
8 -0.07706908  9.89168721  1.489117272  1.121958534   0.5972500  0.38229882
9 -0.11987148  0.12139112  1.144890940  1.278183408   3.7163298  5.38114572
     sum_meth ageing_score mean_hl_hours     mean_mt       ratio
1  0.74099573   -0.1319528    0.06961253 -0.41431559 -0.36779085
2  0.09100790   -0.1498171    2.16798933  0.25840785 -0.41407991
3 17.56155324   -0.0365172   -0.52727817  0.52352412  1.75461979
4 -0.20914633   -0.1594968   -0.43252306  0.09817507  1.60153788
5 -0.14769109    4.5010575    0.19756813 -0.11777628 -0.27256764
6 -0.13732794   -0.1655811   -0.23984692  0.66578679 -0.46954036
7  0.01468209   -0.1960940   -0.03726127 -1.31346370 -0.24532172
8  0.25472832   -0.3234399   -0.43795545  0.63149076  0.46123044
9  1.41782519   -0.2114706   -0.57580138  0.08094353  0.06095318

Clustering vector:
1433B_HUMAN 1433E_HUMAN 1433F_HUMAN 1433G_HUMAN 1433Z_HUMAN  2AAA_HUMAN 
          7           2           7           7           6           6 
 2ABA_HUMAN 3HIDH_HUMAN  6PGL_HUMAN  AAAT_HUMAN  AATC_HUMAN ABHDA_HUMAN 
          7           6           7           6           6           2 
ACADM_HUMAN  ACBP_HUMAN ACL6A_HUMAN  ACLY_HUMAN  ACON_HUMAN  ACTB_HUMAN 
          7           7           6           6           7           7 
ACTN1_HUMAN ACTN4_HUMAN   ADK_HUMAN  ADNP_HUMAN  AHNK_HUMAN AIMP1_HUMAN 
          2           6           6           4           4           7 
AKA12_HUMAN AL9A1_HUMAN ALDH2_HUMAN ALDOC_HUMAN  ALDR_HUMAN  AMPL_HUMAN 
          2           2           7           7           2           6 
AN32A_HUMAN AN32B_HUMAN AN32E_HUMAN  ANLN_HUMAN  ANM5_HUMAN ANXA5_HUMAN 
          2           2           7           4           6           6 
AP3B1_HUMAN   AQR_HUMAN ARFP1_HUMAN ARI1A_HUMAN  ARP2_HUMAN  ARP3_HUMAN 
          6           6           6           4           7           7 
ASAH1_HUMAN  ASNS_HUMAN AT1B3_HUMAN ATX10_HUMAN  BASI_HUMAN BASP1_HUMAN 
          6           6           1           7           7           4 
BAZ1B_HUMAN BOLA2_HUMAN  BRD4_HUMAN  BROX_HUMAN  BYST_HUMAN  BZW1_HUMAN 
          4           7           4           7           4           6 
 C1TC_HUMAN C2D1A_HUMAN  CALR_HUMAN  CALU_HUMAN CAND1_HUMAN CAPR1_HUMAN 
          6           4           1           7           6           4 
 CATA_HUMAN  CATC_HUMAN  CATD_HUMAN CAZA1_HUMAN  CBR1_HUMAN  CBX3_HUMAN 
          6           2           7           7           1           7 
 CBX5_HUMAN CCAR1_HUMAN CCAR2_HUMAN CCD12_HUMAN CD2AP_HUMAN CDC42_HUMAN 
          4           4           5           4           4           6 
CDC5L_HUMAN CDK12_HUMAN CE152_HUMAN  CH10_HUMAN  CH60_HUMAN  CHD6_HUMAN 
          4           4           6           6           2           7 
 CHD7_HUMAN  CHD8_HUMAN CHRD1_HUMAN CHTOP_HUMAN CKAP4_HUMAN CKAP5_HUMAN 
          4           4           7           4           2           6 
 CLH1_HUMAN CLIC1_HUMAN CLIP1_HUMAN  CLPX_HUMAN   CLU_HUMAN  CNBP_HUMAN 
          7           2           4           6           6           6 
 COPB_HUMAN  COPD_HUMAN COPG1_HUMAN COTL1_HUMAN CPIN1_HUMAN CPSF1_HUMAN 
          7           6           7           2           6           7 
CPSF2_HUMAN CPSF5_HUMAN CPSF7_HUMAN CSK21_HUMAN  CSN6_HUMAN CSTF2_HUMAN 
          9           7           4           7           7           4 
CSTF3_HUMAN  CTR9_HUMAN  CUL1_HUMAN  CUL3_HUMAN CUL4A_HUMAN CWC15_HUMAN 
          6           4           6           6           6           8 
CX6B1_HUMAN  CYBP_HUMAN DAZP1_HUMAN   DCK_HUMAN  DDB1_HUMAN DDX21_HUMAN 
          6           6           4           6           6           4 
DDX42_HUMAN DDX46_HUMAN   DEK_HUMAN  DHE3_HUMAN DHX15_HUMAN DHX36_HUMAN 
          4           7           4           2           6           6 
 DHX9_HUMAN DIDO1_HUMAN  DKC1_HUMAN  DLDH_HUMAN DNJA2_HUMAN DNJB1_HUMAN 
          1           4           6           6           9           7 
DNJC1_HUMAN DNLI3_HUMAN DNMT1_HUMAN  DRG1_HUMAN  DRG2_HUMAN DSRAD_HUMAN 
          4           6           6           6           7           7 
DX39B_HUMAN  ECH1_HUMAN  ECHA_HUMAN  ECHM_HUMAN  EDC4_HUMAN  EDF1_HUMAN 
          2           1           1           1           4           4 
 EEA1_HUMAN  EF1B_HUMAN  EF1G_HUMAN   EF2_HUMAN  EFGM_HUMAN  EFTU_HUMAN 
          6           7           7           6           6           1 
EIF3A_HUMAN EIF3E_HUMAN EIF3I_HUMAN EIF3J_HUMAN EIF3M_HUMAN   ELL_HUMAN 
          4           6           6           4           7           4 
 ENOA_HUMAN  ENPL_HUMAN ERAP1_HUMAN ERCC3_HUMAN   ERH_HUMAN ERP29_HUMAN 
          2           1           6           6           8           7 
 ESTD_HUMAN  ETFA_HUMAN  ETFB_HUMAN  EZRI_HUMAN F10A1_HUMAN F136A_HUMAN 
          6           7           2           7           4           7 
FABP5_HUMAN  FAF1_HUMAN FAH2A_HUMAN   FAS_HUMAN  FEN1_HUMAN  FIP1_HUMAN 
          6           6           2           6           5           4 
FKBP3_HUMAN FKBP4_HUMAN FKBP8_HUMAN  FLNA_HUMAN  FLNB_HUMAN  FPPS_HUMAN 
          6           1           6           6           6           7 
FUBP1_HUMAN FUBP2_HUMAN G3BP1_HUMAN G3BP2_HUMAN   G3P_HUMAN  G6PD_HUMAN 
          4           4           4           4           2           6 
 G6PI_HUMAN GANAB_HUMAN GFPT1_HUMAN  GLYM_HUMAN GOGB1_HUMAN GRP75_HUMAN 
          2           7           7           6           6           7 
GRPE1_HUMAN  GSHR_HUMAN GSLG1_HUMAN GSTO1_HUMAN GSTP1_HUMAN GT251_HUMAN 
          1           2           6           7           7           1 
 HCD2_HUMAN HDDC2_HUMAN HEAT1_HUMAN  HEM6_HUMAN HNRH3_HUMAN HNRL1_HUMAN 
          2           6           6           6           6           4 
HNRL2_HUMAN HNRPF_HUMAN HNRPL_HUMAN HNRPM_HUMAN HNRPQ_HUMAN HNRPR_HUMAN 
          7           7           6           6           7           7 
HNRPU_HUMAN HS105_HUMAN HS90A_HUMAN HS90B_HUMAN HSP74_HUMAN HSP7C_HUMAN 
          7           6           5           5           7           5 
 HXK2_HUMAN HYOU1_HUMAN IDH3A_HUMAN  IDI1_HUMAN  IF2A_HUMAN  IF2B_HUMAN 
          6           7           7           6           6           6 
 IF2G_HUMAN  IF2P_HUMAN IF4A3_HUMAN IF4G1_HUMAN   IF5_HUMAN   IF6_HUMAN 
          6           4           6           4           7           6 
 ILEU_HUMAN  ILF3_HUMAN  IMA4_HUMAN  IMA5_HUMAN  IMB1_HUMAN  INCE_HUMAN 
          2           4           6           6           6           4 
 IPO7_HUMAN  IPYR_HUMAN IQGA1_HUMAN  ITB1_HUMAN   IVD_HUMAN  IWS1_HUMAN 
          6           9           6           1           1           9 
 JUND_HUMAN  KAD2_HUMAN  KAD3_HUMAN KHDR1_HUMAN  KINH_HUMAN  KPYM_HUMAN 
          4           2           2           4           6           6 
 KTHY_HUMAN  KYNU_HUMAN LACB2_HUMAN LAP2A_HUMAN LARP1_HUMAN LASP1_HUMAN 
          6           6           6           2           4           4 
   LA_HUMAN   LBR_HUMAN  LDHA_HUMAN  LDHB_HUMAN  LEG1_HUMAN LETM1_HUMAN 
          2           7           6           2           1           6 
 LGUL_HUMAN  LIS1_HUMAN LKHA4_HUMAN  LMNA_HUMAN LMNB1_HUMAN  LONM_HUMAN 
          6           6           6           4           2           6 
LPPRC_HUMAN LRC47_HUMAN LRC59_HUMAN LS14A_HUMAN  LSM6_HUMAN  LSM8_HUMAN 
          7           7           1           4           6           8 
LUZP1_HUMAN  LYAR_HUMAN LYPA1_HUMAN  MANF_HUMAN  MAOM_HUMAN  MAP2_HUMAN 
          4           9           6           6           7           7 
 MAP4_HUMAN MARCS_HUMAN MAT2B_HUMAN MATR3_HUMAN  MBD3_HUMAN  MCES_HUMAN 
          4           1           6           4           4           6 
 MCM2_HUMAN  MCM4_HUMAN  MCM5_HUMAN  MCM6_HUMAN MCMBP_HUMAN MD2L1_HUMAN 
          7           6           6           6           7           6 
 MDC1_HUMAN  MDHC_HUMAN  MDHM_HUMAN  MDN1_HUMAN MECP2_HUMAN MEF2D_HUMAN 
          4           2           2           6           2           4 
METK2_HUMAN   MIF_HUMAN  MK01_HUMAN  MK14_HUMAN   MNT_HUMAN  MOES_HUMAN 
          6           6           5           5           8           1 
 MPPB_HUMAN  MPRD_HUMAN  MSH6_HUMAN  MYH9_HUMAN MYPT1_HUMAN NAA15_HUMAN 
          6           6           6           7           4           6 
NDUS1_HUMAN NDUS3_HUMAN  NEB2_HUMAN NEDD8_HUMAN NIPS1_HUMAN  NIT2_HUMAN 
          7           6           3           7           6           7 
 NMT1_HUMAN NOLC1_HUMAN  NONO_HUMAN NP1L4_HUMAN   NPM_HUMAN NPTX1_HUMAN 
          6           4           7           7           5           6 
  NSF_HUMAN NU133_HUMAN NUCB1_HUMAN  NUCL_HUMAN NUP50_HUMAN NUP88_HUMAN 
          6           6           4           4           7           6 
 ODO2_HUMAN  ODP2_HUMAN  ODPA_HUMAN  ODPB_HUMAN P4HA1_HUMAN  P5CS_HUMAN 
          2           6           6           6           7           7 
 P66A_HUMAN PA2G4_HUMAN PABP1_HUMAN PAIRB_HUMAN PARK7_HUMAN PARP1_HUMAN 
          4           7           7           4           5           5 
PCKGM_HUMAN  PCNA_HUMAN PDC6I_HUMAN PDCD5_HUMAN PDCD6_HUMAN PDIA1_HUMAN 
          7           5           6           7           6           6 
PDIA3_HUMAN PDIA4_HUMAN PDIA6_HUMAN PDLI1_HUMAN PDS5B_HUMAN PEBP1_HUMAN 
          1           1           7           6           6           6 
PELP1_HUMAN  PFD2_HUMAN  PFD4_HUMAN  PFD6_HUMAN PGAM1_HUMAN  PGK1_HUMAN 
          7           7           7           7           1           2 
 PGM1_HUMAN  PGM2_HUMAN PGRC2_HUMAN  PIMT_HUMAN PITH1_HUMAN PLBL2_HUMAN 
          2           2           7           7           6           6 
 PLEC_HUMAN PLOD1_HUMAN PLPL6_HUMAN PLRG1_HUMAN  PNPH_HUMAN PNPT1_HUMAN 
          7           6           6           6           6           7 
 PP1A_HUMAN PP1RA_HUMAN PPCEL_HUMAN  PPCE_HUMAN  PPIA_HUMAN  PPIB_HUMAN 
          6           4           6           6           7           1 
 PPIH_HUMAN PRDX1_HUMAN PRDX2_HUMAN PRDX3_HUMAN PRDX5_HUMAN PRDX6_HUMAN 
          6           7           2           2           7           1 
PRKDC_HUMAN PROF1_HUMAN PRP19_HUMAN  PRP4_HUMAN  PRP6_HUMAN  PRP8_HUMAN 
          5           1           7           7           6           7 
 PRS4_HUMAN PRS6B_HUMAN  PRS7_HUMAN  PRS8_HUMAN  PSA1_HUMAN  PSA2_HUMAN 
          6           6           6           6           6           2 
 PSA3_HUMAN  PSA5_HUMAN  PSA7_HUMAN   PSA_HUMAN  PSB1_HUMAN PSD11_HUMAN 
          6           6           6           6           6           6 
PSD12_HUMAN PSMD1_HUMAN PSMD2_HUMAN PSMD3_HUMAN PSMD5_HUMAN PSME1_HUMAN 
          6           6           6           6           6           7 
PSME3_HUMAN PTBP1_HUMAN PUF60_HUMAN  PUR6_HUMAN  PUR9_HUMAN  PURA_HUMAN 
          6           7           7           6           7           4 
 PUS7_HUMAN   PYC_HUMAN  QCR7_HUMAN   QOR_HUMAN RAB14_HUMAN RAB5C_HUMAN 
          6           6           2           6           6           7 
 RAC1_HUMAN  RADI_HUMAN RAE1L_HUMAN RAGP1_HUMAN RBM12_HUMAN RBM26_HUMAN 
          6           4           6           6           4           4 
 RBM4_HUMAN RBM8A_HUMAN  RCC2_HUMAN RD23A_HUMAN RD23B_HUMAN RECQ1_HUMAN 
          7           4           4           4           4           7 
RENT1_HUMAN REPS1_HUMAN  RFA1_HUMAN  RFA2_HUMAN  RL10_HUMAN  RL12_HUMAN 
          9           4           5           5           6           1 
 RL14_HUMAN RL23A_HUMAN RL27A_HUMAN  RL27_HUMAN  RL30_HUMAN   RL3_HUMAN 
          7           6           6           6           6           6 
  RL4_HUMAN   RL5_HUMAN   RL7_HUMAN  RM12_HUMAN  RM49_HUMAN  ROA2_HUMAN 
          6           6           6           2           6           7 
 RPA1_HUMAN  RPA2_HUMAN  RPB2_HUMAN  RPN1_HUMAN RRP44_HUMAN  RS12_HUMAN 
          6           6           6           6           7           9 
 RS13_HUMAN  RS20_HUMAN  RS28_HUMAN   RS3_HUMAN   RS6_HUMAN   RS8_HUMAN 
          6           6           1           5           4           6 
  RS9_HUMAN  RSF1_HUMAN  RSU1_HUMAN  RT29_HUMAN  RTCB_HUMAN  RU17_HUMAN 
          6           4           6           6           6           4 
 RU2B_HUMAN S10A6_HUMAN SAFB1_HUMAN SAFB2_HUMAN  SAHH_HUMAN   SAP_HUMAN 
          6           2           4           4           6           6 
 SBDS_HUMAN SCOT1_HUMAN  SERC_HUMAN SERPH_HUMAN   SET_HUMAN  SF01_HUMAN 
          6           2           6           7           4           4 
SF3A1_HUMAN SF3A3_HUMAN SF3B1_HUMAN SF3B2_HUMAN SF3B3_HUMAN SF3B5_HUMAN 
          4           7           6           4           6           8 
 SFPQ_HUMAN  SGT1_HUMAN SIN3A_HUMAN SLIRP_HUMAN SMC1A_HUMAN  SMC3_HUMAN 
          4           6           5           7           6           7 
SMCA4_HUMAN SMCA5_HUMAN  SMD1_HUMAN  SMD2_HUMAN SMRC1_HUMAN  SND1_HUMAN 
          4           6           6           2           4           7 
SNR40_HUMAN SNUT1_HUMAN  SNX3_HUMAN  SNX6_HUMAN  SODC_HUMAN SP16H_HUMAN 
          6           4           6           6           5           6 
 SPB6_HUMAN  SPSY_HUMAN SPT5H_HUMAN SPTB2_HUMAN SPTN1_HUMAN SR140_HUMAN 
          2           1           4           7           7           4 
SRP14_HUMAN SRPK1_HUMAN  SRRT_HUMAN SRS11_HUMAN SRSF6_HUMAN SRSF7_HUMAN 
          6           4           7           4           4           4 
SSRP1_HUMAN STAG2_HUMAN STAT1_HUMAN STIP1_HUMAN STRAP_HUMAN SUCB1_HUMAN 
          4           6           5           7           7           7 
SUCB2_HUMAN SUMO2_HUMAN  SYAM_HUMAN  SYDM_HUMAN  SYFB_HUMAN  SYIM_HUMAN 
          7           4           7           6           6           6 
 SYLM_HUMAN SYMPK_HUMAN  T2EB_HUMAN TACC3_HUMAN TAGL2_HUMAN TCEA1_HUMAN 
          6           6           7           4           7           6 
 TCOF_HUMAN  TCP4_HUMAN  TCPA_HUMAN  TCPD_HUMAN  TCPE_HUMAN  TCPH_HUMAN 
          4           4           6           6           7           6 
 TCPZ_HUMAN TCRG1_HUMAN  TCTP_HUMAN  TERA_HUMAN TFCP2_HUMAN  TFR1_HUMAN 
          6           7           7           5           6           6 
 THIC_HUMAN  THIL_HUMAN  THIM_HUMAN THOC1_HUMAN THOC2_HUMAN THOC6_HUMAN 
          7           2           2           1           6           6 
TIF1B_HUMAN   TKT_HUMAN  TLN1_HUMAN TMOD3_HUMAN TNPO1_HUMAN  TOP1_HUMAN 
          7           2           6           6           7           6 
TPD54_HUMAN  TPIS_HUMAN  TPM4_HUMAN   TPR_HUMAN  TPX2_HUMAN TR150_HUMAN 
          4           2           7           4           4           4 
TRIPC_HUMAN TXD12_HUMAN TXLNA_HUMAN TXND5_HUMAN  TYPH_HUMAN  TYY1_HUMAN 
          4           7           4           1           6           4 
U2AF2_HUMAN U3IP2_HUMAN  U520_HUMAN  U5S1_HUMAN UB2L3_HUMAN  UBA1_HUMAN 
          7           9           6           6           6           7 
 UBA6_HUMAN  UBL5_HUMAN  UBR5_HUMAN UBXN1_HUMAN  UFC1_HUMAN  UGPA_HUMAN 
          6           6           6           4           6           2 
 VASP_HUMAN VATB2_HUMAN VATC1_HUMAN VIGLN_HUMAN  VIME_HUMAN  VINC_HUMAN 
          4           6           6           6           7           2 
VPS29_HUMAN VPS35_HUMAN VPS4B_HUMAN  VTA1_HUMAN  WDR1_HUMAN WDR26_HUMAN 
          6           6           6           7           6           6 
 WDR5_HUMAN WIPF1_HUMAN  XPO1_HUMAN  XPO7_HUMAN  XPOT_HUMAN XRCC5_HUMAN 
          2           4           6           7           6           5 
XRCC6_HUMAN  XRN2_HUMAN ZC3H4_HUMAN ZC3HF_HUMAN ZCHC8_HUMAN   ZFR_HUMAN 
          5           6           4           7           4           6 
ZMAT2_HUMAN ZN638_HUMAN  ZPR1_HUMAN  CKS2_HUMAN FBX28_HUMAN  PLK1_HUMAN 
          6           4           7           6           4           5 
SHCBP_HUMAN UBE2S_HUMAN PANK3_HUMAN  HXA9_HUMAN 
          9           6           6           4 

Within cluster sum of squares by cluster:
[1] 366.0494 325.3350   0.0000 420.8315 140.1416 578.6450 390.6206 145.5366
[9] 574.2322
 (between_SS / total_SS =  55.7 %)

Available components:

[1] "cluster"      "centers"      "totss"        "withinss"     "tot.withinss"
[6] "betweenss"    "size"         "iter"         "ifault"      

Evaluation of results:

             Length Class  Mode   
cluster      604    -none- numeric
centers       99    -none- numeric
totss          1    -none- numeric
withinss       9    -none- numeric
tot.withinss   1    -none- numeric
betweenss      1    -none- numeric
size           9    -none- numeric
iter           1    -none- numeric
ifault         1    -none- numeric

Getting the cluster members:

Heatmap to see the patterns:

B cells cytoplasm

Extra B cells stuff:

Joining everything:

K-means clustering with 21 clusters of sizes 112, 78, 3, 58, 2, 2, 113, 2, 1, 4, 3, 2, 1, 64, 1, 24, 10, 3, 14, 76, 1

Cluster means:
   sum_acetyl_cyto_old sum_acetyl_cyto_young sum_AGEs_cyto_old
1          -0.05574548            0.00329445       -0.08940024
2          -0.08874043           -0.11157139       -0.09413095
3          -0.12119350           -0.12346193       -0.09413095
4          -0.12119350           -0.12346193       -0.09413095
5          13.90628726           -0.12346193       -0.09413095
6          -0.12119350           -0.12346193       -0.09413095
7          -0.09153319           -0.05108593       -0.09159079
8           3.22038695            2.45209929       -0.09413095
9          -0.12119350           -0.12346193       -0.09413095
10         -0.01680829            0.12353901       11.00743245
11         -0.12119350           -0.12346193       -0.09413095
12         -0.12119350           -0.12346193       -0.09413095
13         -0.12119350           -0.12346193       -0.09413095
14         -0.11103540           -0.07462663       -0.09413095
15         -0.12119350           -0.12346193       -0.09413095
16          0.12260427            0.27846851       -0.09413095
17          0.28286779            0.14644827       -0.09413095
18         -0.06263037            0.29057995       -0.09413095
19         -0.12119350           -0.12346193       -0.09413095
20         -0.10777267           -0.07542071        0.02176426
21          9.33752830           20.93774457       -0.09413095
   sum_AGEs_cyto_young sum_Kacyl_cyto_old sum_Kacyl_cyto_young
1          -0.05935759        -0.06877440          -0.07233615
2          -0.05719505        -0.07272657          -0.07233615
3          -0.05935759        -0.07272657          -0.07233615
4          -0.05935759        -0.07272657          -0.07233615
5          -0.05935759        -0.07272657          -0.07233615
6          -0.05935759        -0.07272657          -0.07233615
7          -0.05935759        -0.07272657          -0.07233615
8          16.89193272        -0.07272657          -0.07233615
9          -0.05935759        -0.07272657          -0.07233615
10         -0.05935759        -0.07272657          -0.07233615
11         -0.05935759        -0.07272657          -0.07233615
12         -0.05935759        -0.07272657          -0.07233615
13         -0.05935759        21.36623903          -0.07233615
14         -0.05935759        -0.07272657          -0.07233615
15         -0.05935759        -0.07272657          -0.07233615
16         -0.05935759         0.47809656          -0.07233615
17         -0.05935759        -0.07272657          -0.07233615
18         -0.05935759         1.66415476          13.76798062
19         -0.05935759        -0.07272657          -0.07233615
20         -0.05935759        -0.05387072          -0.07233615
21         -0.05935759        -0.07272657          -0.07233615
   sum_oxPTMs_cyto_old sum_oxPTMs_cyto_young sum_phospho_cyto_old
1         -0.112085460           -0.09918071         -0.098777134
2         -0.265586912           -0.20660060         -0.073519674
3         -0.209134749           -0.07494835          0.536193327
4         -0.362966537           -0.26528859          0.009182094
5          0.808574493           -0.29676601         -0.099410470
6         -0.408605725           -0.29676601         -0.099410470
7         -0.308538049           -0.23191416         -0.096112779
8         -0.019765990            0.39012831         -0.099410470
9         -0.408605725           -0.29676601         -0.099410470
10         0.803963042            1.11774238          0.063892017
11         0.308428889            0.47738665         -0.099410470
12         4.126115569            1.02149456         15.806874819
13        -0.003604577            0.05001814         -0.099410470
14        -0.336511461           -0.23083996         -0.071534963
15         7.047457992           19.46413123         -0.099410470
16         3.136930356            1.46273519          0.017747491
17         0.425964392            0.63295550         -0.099410470
18         1.362915040            0.53657631         -0.099410470
19         0.028816197           -0.06170822          0.541820554
20         0.104365595            0.19965507         -0.094745516
21        -0.408605725           -0.29676601         -0.099410470
   sum_phospho_cyto_young sum_ubiq_cyto_old sum_ubiq_cyto_young
1             -0.03181933      -0.122541632         -0.05940235
2             -0.09103226      -0.152078921         -0.11756757
3              0.69272361      -0.157456354         -0.11756757
4              0.01491517      -0.157456354         -0.11517610
5             -0.09166779      -0.157456354         -0.11756757
6             -0.09166779      -0.157456354         -0.11756757
7             -0.08353426      -0.125407871         -0.11726220
8             -0.09166779      -0.157456354         -0.11756757
9             21.27729407      -0.157456354         -0.11756757
10            -0.09166779       0.357816593          0.49347001
11            -0.09166779      -0.157456354         -0.11756757
12             2.86491891       2.733814847         -0.11756757
13            -0.09166779      -0.157456354         -0.11756757
14            -0.03506203      -0.135021277         -0.11756757
15            -0.09166779      -0.157456354         -0.11756757
16            -0.09166779      -0.007346495          0.12503633
17            -0.09166779       5.998705925          4.69174395
18            -0.09166779       0.362500082         -0.11756757
19             0.29679424      -0.143677467         -0.11756757
20            -0.09078273      -0.075455464         -0.05919508
21            -0.09166779      -0.157456354         -0.11756757
   sum_meth_cyto_old sum_meth_cyto_young mean_hl_hours     mean_mt      ratio
1        -0.08078889         -0.05931590    0.06896626 -1.22089828 -0.5040832
2        -0.11003022         -0.11567541   -0.23841393  0.69935919  0.3224522
3        11.78719653         -0.11989850   -0.19081638  0.55857537  0.6499053
4        -0.08165294         -0.09875645   -0.32407146  0.59602937  1.8202854
5        -0.11592231         -0.11989850    0.10063362  0.57238851  0.9879969
6        -0.11592231         -0.11989850   11.86382142  0.59968265  1.7391539
7        -0.04832724         -0.11989850   -0.42802174  0.70328811 -0.6608278
8        -0.11592231         -0.11989850   -0.29053861 -0.08819093 -0.6748889
9        -0.11592231         -0.11989850   -0.78254565 -0.24933640  1.3617489
10        0.04887079          0.36215814    1.16493044  0.38495787 -0.8216846
11        3.70113164          8.97024141    0.07556561 -0.82212016 -0.5575070
12       -0.11592231         -0.11989850   -0.60989997  0.65943529  1.1583761
13       -0.11592231         -0.11989850   -0.31678078 -0.29702243 -0.5585838
14       -0.08313114         -0.05971667   -0.19574581 -1.34842749  1.2802011
15       -0.11592231         -0.11989850   -0.28049576 -2.06981847 -0.6663757
16       -0.05358586         -0.05959855    0.42460265  0.02048904 -0.5747182
17       -0.11592231         -0.11989850   -0.08155507 -0.08777467 -0.3851672
18       -0.11592231          5.08009253   -0.14871290  0.53509817 -0.3345709
19       -0.11592231         -0.11989850    2.62559045  0.42152269 -0.6541450
20       -0.10138794          0.01672509    0.25031861  0.59124498 -0.7411695
21       -0.11592231         -0.11989850    0.78896286  0.77381814 -0.9428366

Clustering vector:
1433B_HUMAN 1433E_HUMAN 1433F_HUMAN 1433G_HUMAN 1433Z_HUMAN  2AAA_HUMAN 
          1          20           1           1          20           7 
 2ABA_HUMAN 3HIDH_HUMAN  6PGL_HUMAN  AAAT_HUMAN  AATC_HUMAN ABHDA_HUMAN 
          1          19           1           7           7          19 
ACADM_HUMAN  ACBP_HUMAN ACL6A_HUMAN  ACLY_HUMAN  ACON_HUMAN ACTN1_HUMAN 
         17           1          20           7           1          19 
ACTN4_HUMAN   ADK_HUMAN  ADNP_HUMAN  AHNK_HUMAN AIMP1_HUMAN AL9A1_HUMAN 
         20          19           2           4           1          17 
ALDH2_HUMAN ALDOC_HUMAN  ALDR_HUMAN  AMPL_HUMAN AN32A_HUMAN AN32B_HUMAN 
          1           1           1          20           2           2 
AN32E_HUMAN  ANM5_HUMAN ANXA5_HUMAN AP3B1_HUMAN   AQR_HUMAN ARFP1_HUMAN 
         14           7          20           2           7           2 
ARI1A_HUMAN  ARP2_HUMAN  ARP3_HUMAN  ASNS_HUMAN ATX10_HUMAN  B2MG_HUMAN 
          4          16           1           7          17           7 
 BASI_HUMAN BASP1_HUMAN BAZ1B_HUMAN   BIP_HUMAN BOLA2_HUMAN  BRD4_HUMAN 
          1          14           2           1          15           4 
 BYST_HUMAN  BZW1_HUMAN  C1TC_HUMAN C2D1A_HUMAN  CALR_HUMAN CAND1_HUMAN 
          2           7           7          14          14          20 
CAPR1_HUMAN  CATA_HUMAN  CATD_HUMAN CAZA1_HUMAN  CBR1_HUMAN  CBX3_HUMAN 
         14          16           1          16           1          14 
 CBX5_HUMAN CCAR1_HUMAN CCAR2_HUMAN CD2AP_HUMAN CDC42_HUMAN CDC5L_HUMAN 
         14          14          17          14           7           4 
CDC73_HUMAN CDK12_HUMAN  CH10_HUMAN  CH60_HUMAN CHRD1_HUMAN CHTOP_HUMAN 
          2           4          20          20           1           4 
CKAP4_HUMAN CKAP5_HUMAN  CLH1_HUMAN CLIC1_HUMAN CLIP1_HUMAN  CLPX_HUMAN 
          2           2           1          20           4           7 
  CLU_HUMAN  CNBP_HUMAN  COPB_HUMAN  COPD_HUMAN COPG1_HUMAN COTL1_HUMAN 
          7          17           1           2           1          16 
CPIN1_HUMAN CPSF1_HUMAN CPSF2_HUMAN CPSF5_HUMAN CPSF7_HUMAN  CSN6_HUMAN 
          7           1           7           1           4           1 
CSTF2_HUMAN CSTF3_HUMAN  CTR9_HUMAN  CUL1_HUMAN  CUL3_HUMAN CUL4A_HUMAN 
          4           7           2           7           7           7 
CWC15_HUMAN  CYBP_HUMAN DAZP1_HUMAN   DCK_HUMAN  DDB1_HUMAN DDX21_HUMAN 
          5           7           4          16           7           2 
DDX42_HUMAN DDX46_HUMAN   DEK_HUMAN  DHE3_HUMAN DHX15_HUMAN DHX36_HUMAN 
         14          14          14          19           1           7 
 DHX9_HUMAN DIDO1_HUMAN  DKC1_HUMAN  DLDH_HUMAN DNJA1_HUMAN DNJA2_HUMAN 
          7           4           2          20           7          17 
DNJB1_HUMAN DNLI3_HUMAN DNMT1_HUMAN  DRG1_HUMAN  DRG2_HUMAN DSRAD_HUMAN 
         14           7           2           7           1          14 
DX39B_HUMAN  ECH1_HUMAN  ECHA_HUMAN  ECHM_HUMAN  EDC4_HUMAN  EDF1_HUMAN 
          1          16          16          16           2          14 
 EEA1_HUMAN  EF1B_HUMAN  EF1G_HUMAN   EF2_HUMAN  EFGM_HUMAN  EFTU_HUMAN 
          2           1           1           7           3          16 
EIF3A_HUMAN EIF3E_HUMAN EIF3I_HUMAN EIF3J_HUMAN EIF3M_HUMAN  ELF1_HUMAN 
          2          20           7          14           1           9 
 ENOA_HUMAN  ENPL_HUMAN ERAP1_HUMAN ERCC3_HUMAN   ERH_HUMAN ERP29_HUMAN 
          1           1          20           7           7           1 
 ESTD_HUMAN  ETFA_HUMAN  ETFB_HUMAN  EZRI_HUMAN F10A1_HUMAN F136A_HUMAN 
         20           1          20          14          14           1 
FABP5_HUMAN  FAF1_HUMAN   FAS_HUMAN  FEN1_HUMAN FKBP3_HUMAN FKBP4_HUMAN 
          7           2           7           1           2           7 
FKBP8_HUMAN  FLNA_HUMAN  FLNB_HUMAN  FPPS_HUMAN FUBP1_HUMAN FUBP2_HUMAN 
          2           2          20           1          14           4 
G3BP1_HUMAN G3BP2_HUMAN   G3P_HUMAN  G6PD_HUMAN  G6PI_HUMAN GANAB_HUMAN 
         14           4           1           7           1           1 
GFPT1_HUMAN  GLYM_HUMAN GOGB1_HUMAN GRP75_HUMAN GRPE1_HUMAN  GSHR_HUMAN 
          1           7           2          11           1          19 
GSLG1_HUMAN GSTO1_HUMAN GSTP1_HUMAN GT251_HUMAN  HCD2_HUMAN HDDC2_HUMAN 
          7           1           1           7          20           5 
HEAT1_HUMAN  HEM6_HUMAN HNRH3_HUMAN HNRL1_HUMAN HNRL2_HUMAN HNRPF_HUMAN 
          7           7           2           4          14           1 
HNRPL_HUMAN HNRPM_HUMAN HNRPQ_HUMAN HNRPR_HUMAN HNRPU_HUMAN HS105_HUMAN 
          2           2          14          14          14           2 
HS90A_HUMAN HS90B_HUMAN HSP74_HUMAN HSP7C_HUMAN  HXK2_HUMAN HYOU1_HUMAN 
          2           1           1           1           7           1 
I2BP2_HUMAN IDH3A_HUMAN  IDI1_HUMAN  IF2A_HUMAN  IF2B_HUMAN  IF2G_HUMAN 
         14           1           7           7           2           7 
 IF2P_HUMAN IF4A3_HUMAN IF4G1_HUMAN   IF5_HUMAN   IF6_HUMAN  ILEU_HUMAN 
          4           7           4           1           7          16 
 ILF3_HUMAN  IMA1_HUMAN  IMA5_HUMAN  IMB1_HUMAN  IPO7_HUMAN  IPYR_HUMAN 
         14           7           7          20          20          17 
IQGA1_HUMAN  ITB1_HUMAN   IVD_HUMAN  IWS1_HUMAN  JUND_HUMAN  KAD2_HUMAN 
         16           7          20           4          14          20 
 KAD3_HUMAN KHDR1_HUMAN  KINH_HUMAN  KPYM_HUMAN  KTHY_HUMAN  KYNU_HUMAN 
         19          14          17           7           7          16 
LAP2A_HUMAN LARP1_HUMAN LASP1_HUMAN    LA_HUMAN   LBR_HUMAN  LDHA_HUMAN 
         14           4           4           2           1           7 
 LDHB_HUMAN  LEG1_HUMAN LETM1_HUMAN  LGUL_HUMAN  LIS1_HUMAN LKHA4_HUMAN 
          7           1           2          20          20          10 
 LMNA_HUMAN LMNB1_HUMAN  LONM_HUMAN LPPRC_HUMAN LRC47_HUMAN LRC59_HUMAN 
          4           6           7           1           1          14 
LS14A_HUMAN  LSM6_HUMAN  LSM8_HUMAN  LYAR_HUMAN  MANF_HUMAN  MAOM_HUMAN 
          4          20          21           2           7          20 
 MAP2_HUMAN  MAP4_HUMAN MARCS_HUMAN MAT2B_HUMAN MATR3_HUMAN  MCES_HUMAN 
         14           4           4           7           4           2 
 MCM2_HUMAN  MCM4_HUMAN  MCM5_HUMAN  MCM6_HUMAN MCMBP_HUMAN  MDC1_HUMAN 
          1           7           7           7           1           4 
 MDHC_HUMAN  MDHM_HUMAN  MDN1_HUMAN MECP2_HUMAN METK2_HUMAN   MIF_HUMAN 
         20          19           7           6           7          20 
 MK01_HUMAN  MOES_HUMAN  MPPB_HUMAN  MPRD_HUMAN  MSH6_HUMAN  MTA2_HUMAN 
         20          16           7           7           7           1 
 MYH9_HUMAN MYPT1_HUMAN NAA15_HUMAN NDUS1_HUMAN NDUS3_HUMAN  NEB2_HUMAN 
          1           4           7           1          20           4 
NEDD8_HUMAN NIPS1_HUMAN  NIT2_HUMAN  NMT1_HUMAN NOLC1_HUMAN  NONO_HUMAN 
          1          19           1           2          14          14 
NP1L4_HUMAN   NPM_HUMAN   NSF_HUMAN NU133_HUMAN NU153_HUMAN NUCB1_HUMAN 
          1          14           7           7           4           4 
 NUCL_HUMAN NUP50_HUMAN NUP88_HUMAN  ODO2_HUMAN  ODP2_HUMAN  ODPA_HUMAN 
         14          14           7          19          19          20 
 ODPB_HUMAN  P5CS_HUMAN  P66A_HUMAN  P66B_HUMAN PA2G4_HUMAN PABP1_HUMAN 
         20           1           4           4           1          14 
PAIRB_HUMAN PARK7_HUMAN PARP1_HUMAN PCKGM_HUMAN  PCNA_HUMAN PDC6I_HUMAN 
         14          20           1           1           1           2 
PDCD4_HUMAN PDCD5_HUMAN PDCD6_HUMAN PDIA1_HUMAN PDIA3_HUMAN PDIA4_HUMAN 
         12          14           7          20           1           1 
PDIA6_HUMAN PDLI1_HUMAN PDS5B_HUMAN PEBP1_HUMAN PELP1_HUMAN  PFD2_HUMAN 
          1          16           2           3          14          14 
 PFD3_HUMAN  PFD5_HUMAN PGAM1_HUMAN  PGK1_HUMAN  PGM1_HUMAN  PGM2_HUMAN 
          1          20          11          10          19          19 
PGRC2_HUMAN  PIMT_HUMAN PITH1_HUMAN  PLEC_HUMAN PLPL6_HUMAN PLRG1_HUMAN 
          1          11           2           1           7           2 
 PNPH_HUMAN PNPT1_HUMAN  PP1A_HUMAN PP1RA_HUMAN  PPCE_HUMAN  PPIA_HUMAN 
         16           1           7           4          16           1 
 PPIB_HUMAN  PPIH_HUMAN PRDX1_HUMAN PRDX2_HUMAN PRDX3_HUMAN PRDX5_HUMAN 
          1           7           1          20          19           1 
PRDX6_HUMAN PRKDC_HUMAN PROF1_HUMAN PRP19_HUMAN  PRP4_HUMAN  PRP6_HUMAN 
         18          20          16           1           1           2 
 PRP8_HUMAN  PRS4_HUMAN PRS6B_HUMAN  PRS7_HUMAN  PRS8_HUMAN  PSA1_HUMAN 
          1          20          20          20           7           7 
 PSA2_HUMAN  PSA3_HUMAN  PSA5_HUMAN  PSA7_HUMAN   PSA_HUMAN  PSB1_HUMAN 
         20           8          20          20          20          20 
PSD11_HUMAN PSD12_HUMAN PSMD1_HUMAN PSMD2_HUMAN PSMD3_HUMAN PSMD5_HUMAN 
         20          17          20           7           2          20 
PSME1_HUMAN PSME3_HUMAN PTBP1_HUMAN PUF60_HUMAN  PUR6_HUMAN  PUR9_HUMAN 
          1           7           1           1          10           1 
 PURA_HUMAN  PUS7_HUMAN  QCR7_HUMAN   QKI_HUMAN   QOR_HUMAN RAB14_HUMAN 
          2           7          20           1          20          20 
RAB5C_HUMAN RAD21_HUMAN  RADI_HUMAN RAE1L_HUMAN RAGP1_HUMAN RBBP4_HUMAN 
          1           4          14           7           2          18 
RBM12_HUMAN RBM26_HUMAN RBM8A_HUMAN  RCC2_HUMAN RD23A_HUMAN RD23B_HUMAN 
          4           4          14          20           4           4 
RECQ1_HUMAN RENT1_HUMAN REPS1_HUMAN  RFA1_HUMAN  RFA2_HUMAN  RL10_HUMAN 
          1          17           4          20           2           7 
 RL12_HUMAN  RL14_HUMAN RL23A_HUMAN RL27A_HUMAN  RL27_HUMAN  RL30_HUMAN 
         13          14           2           2           7           7 
  RL3_HUMAN   RL4_HUMAN   RL5_HUMAN   RL7_HUMAN  RM12_HUMAN  RM49_HUMAN 
         20           2          20           7          16           2 
 ROA2_HUMAN  RPA1_HUMAN  RPA2_HUMAN  RPB2_HUMAN  RPN1_HUMAN RRP44_HUMAN 
         14           7           7           7          20           1 
 RS12_HUMAN  RS13_HUMAN  RS20_HUMAN  RS28_HUMAN   RS3_HUMAN   RS6_HUMAN 
         16           7          18           1           7           2 
  RS8_HUMAN   RS9_HUMAN  RSF1_HUMAN  RSU1_HUMAN  RT29_HUMAN  RTCB_HUMAN 
          2           7           4           7           7          20 
 RU17_HUMAN  RU2B_HUMAN S10A6_HUMAN SAFB1_HUMAN SAFB2_HUMAN  SAHH_HUMAN 
          4           2          20           4           4          20 
  SAP_HUMAN  SBDS_HUMAN SCOT1_HUMAN  SERC_HUMAN   SET_HUMAN  SF01_HUMAN 
         20           7           1           7           4          14 
SF3A1_HUMAN SF3A3_HUMAN SF3B1_HUMAN SF3B2_HUMAN SF3B3_HUMAN SF3B5_HUMAN 
          4           1           2          14           7           7 
SF3B6_HUMAN  SFPQ_HUMAN  SGT1_HUMAN SIN3A_HUMAN  SKP1_HUMAN SLIRP_HUMAN 
          7          14           7           2           2           1 
SMC1A_HUMAN  SMC3_HUMAN SMCA4_HUMAN SMCA5_HUMAN SMCE1_HUMAN  SMD1_HUMAN 
          2           1           4           2          14           2 
 SMD2_HUMAN SMRC1_HUMAN  SND1_HUMAN SNR40_HUMAN SNUT1_HUMAN  SNX3_HUMAN 
          2          14           1           7           4           7 
 SNX6_HUMAN  SODC_HUMAN SP16H_HUMAN  SPB6_HUMAN  SPSY_HUMAN SPT5H_HUMAN 
         16          14           2          20           1           2 
SPTB2_HUMAN SPTN1_HUMAN SR140_HUMAN SRP14_HUMAN SRPK1_HUMAN  SRRT_HUMAN 
          1           1          14           2           2          14 
SRS11_HUMAN SRSF6_HUMAN SRSF7_HUMAN SSRP1_HUMAN STAG2_HUMAN STAT1_HUMAN 
          4           4          14           2           2           7 
STIP1_HUMAN STRAP_HUMAN SUCB1_HUMAN SUCB2_HUMAN SUMO2_HUMAN  SYAM_HUMAN 
          1           8           1           1           4           1 
 SYDM_HUMAN  SYFB_HUMAN  SYIM_HUMAN  SYLM_HUMAN SYMPK_HUMAN  T2EB_HUMAN 
         20           7          20           7           2          14 
TAGL2_HUMAN TCEA1_HUMAN  TCOF_HUMAN  TCP4_HUMAN  TCPA_HUMAN  TCPD_HUMAN 
         16           2          14           4          20          20 
 TCPE_HUMAN  TCPH_HUMAN  TCPZ_HUMAN TCRG1_HUMAN  TCTP_HUMAN  TERA_HUMAN 
          1           7          20          14           1          20 
TFCP2_HUMAN  TFR1_HUMAN  TGO1_HUMAN  THIC_HUMAN  THIL_HUMAN  THIM_HUMAN 
          2           7          14          16           1          10 
THOC1_HUMAN THOC2_HUMAN THOC6_HUMAN TIF1B_HUMAN   TKT_HUMAN  TLN1_HUMAN 
          2           2           7          14          20          16 
 TLS1_HUMAN TMOD3_HUMAN TNPO1_HUMAN  TOP1_HUMAN TPD54_HUMAN  TPIS_HUMAN 
         12           2           1           2           2          20 
 TPM4_HUMAN   TPR_HUMAN TR150_HUMAN TRIM4_HUMAN TRIPC_HUMAN TXLNA_HUMAN 
         14           4           4           7           2           4 
TXND5_HUMAN  TYPH_HUMAN  TYY1_HUMAN U2AF2_HUMAN U3IP2_HUMAN  U520_HUMAN 
         20          20           4           1           2           7 
 U5S1_HUMAN UB2L3_HUMAN  UBA1_HUMAN  UBA6_HUMAN  UBR5_HUMAN UBXN1_HUMAN 
          7           7           1          20           2          14 
 UFC1_HUMAN  UGPA_HUMAN  VASP_HUMAN VATB2_HUMAN VATC1_HUMAN VIGLN_HUMAN 
          7          20           4           7          20           7 
 VIME_HUMAN  VINC_HUMAN VPS35_HUMAN VPS4B_HUMAN  VTA1_HUMAN  WDR1_HUMAN 
          1          16           7           2          14          20 
WDR26_HUMAN  WDR5_HUMAN WIPF1_HUMAN  XPO1_HUMAN  XPO7_HUMAN  XPOT_HUMAN 
          7          20           3           7           1          20 
XRCC5_HUMAN XRCC6_HUMAN  XRN2_HUMAN ZC3H4_HUMAN ZC3HF_HUMAN ZCHC8_HUMAN 
          1           1           2           4          14           4 
  ZFR_HUMAN ZMAT2_HUMAN ZN638_HUMAN  ZPR1_HUMAN 
          2           2           4          14 

Within cluster sum of squares by cluster:
 [1] 264.263501  49.700719  56.330656  67.751763  14.481954   5.957289
 [7]  93.836332  37.458926   0.000000  70.944777  48.773712  81.931179
[13]   0.000000  95.965312   0.000000 284.887483 501.054819 206.708688
[19]  77.724892 180.507238   0.000000
 (between_SS / total_SS =  78.0 %)

Available components:

[1] "cluster"      "centers"      "totss"        "withinss"     "tot.withinss"
[6] "betweenss"    "size"         "iter"         "ifault"      

Evaluation of results:

             Length Class  Mode   
cluster      574    -none- numeric
centers      357    -none- numeric
totss          1    -none- numeric
withinss      21    -none- numeric
tot.withinss   1    -none- numeric
betweenss      1    -none- numeric
size          21    -none- numeric
iter           1    -none- numeric
ifault         1    -none- numeric

Getting the cluster members:

Heatmap to see the patterns:

B cells nucleus

Joining everything:

K-means clustering with 15 clusters of sizes 2, 118, 1, 19, 3, 67, 1, 1, 256, 84, 8, 4, 4, 2, 1

Cluster means:
   sum_acetyl_nuc_old sum_acetyl_nuc_young sum_AGEs_nuc_old sum_AGEs_nuc_young
1         -0.11541731          -0.11242369      15.66419292        -0.07108179
2         -0.06994998          -0.05307961      -0.05687595        -0.07108179
3         -0.11541731          -0.11242369      -0.05687595        -0.07108179
4         -0.11286009          -0.10466205      -0.05687595        -0.07108179
5         -0.10516767          -0.10003800      -0.05687595        12.80997311
6         -0.09231730          -0.08899296      -0.05687595        -0.07108179
7          2.09753333           2.15214745      -0.05687595        -0.07108179
8         -0.11541731          -0.11242369      -0.05687595        -0.07108179
9         -0.08620106          -0.07750663      -0.05283677        -0.06348594
10        -0.10961363          -0.10861105      -0.05687595        -0.07108179
11         0.20742960           0.57572820      -0.05687595        -0.07108179
12        -0.11541731          -0.11242369      -0.05687595        -0.07108179
13        11.33648666           9.41483000      -0.05687595        -0.07108179
14         0.05502811           0.03708030      -0.05687595        -0.07108179
15        -0.11541731          -0.11242369      -0.05687595        -0.07108179
   sum_Kacyl_nuc_old sum_Kacyl_nuc_young sum_oxPTMs_nuc_old
1       -0.065972355         -0.05814972         0.70108586
2       -0.065972355         -0.05814972        -0.12810276
3       -0.065972355         -0.05814972        -0.15889308
4        0.031336601         -0.05814972         0.02438703
5        0.041608206          0.06663656         0.10634544
6       -0.064265245         -0.05814972         0.02814247
7       23.161220592         22.75748176        -0.15364260
8       -0.065972355         -0.05814972        -0.01345890
9       -0.049362470         -0.04551319        -0.11624287
10      -0.001151049         -0.05814972         0.11339919
11       0.017891802          0.78916862         0.37806855
12      -0.065972355         -0.05814972         0.00459848
13      -0.065972355         -0.05814972         0.30563327
14       0.828527657         -0.05814972         3.04682942
15      -0.065972355         -0.05814972        21.24552146
   sum_oxPTMs_nuc_young sum_phospho_nuc_old sum_phospho_nuc_young
1           0.053022457         -0.15511903           -0.10343773
2          -0.052151764         -0.15336397           -0.07728052
3          -0.051948502         -0.15511903           -0.10343773
4          -0.040282293         -0.15358583           -0.09706591
5           0.011127166         -0.03384538           -0.06353310
6          -0.035622714          0.05566726           -0.04907495
7          -0.062539574         -0.15511903            0.50980860
8          -0.062539574         -0.15511903            0.68623240
9          -0.053274608         -0.14535574           -0.09708642
10         -0.017575362          0.03591880            0.04804257
11          0.001194004          6.44958126            1.78658449
12         -0.029660501         -0.15511903           -0.10343773
13          0.018254940         -0.15511903           -0.10343773
14          0.340774745          1.07790788            0.08851713
15         23.812745565         -0.15511903           20.73258641
   sum_ubiq_nuc_old sum_ubiq_nuc_young sum_meth_nuc_old sum_meth_nuc_young
1      -0.058809225        -0.06371423      -0.09210118       -0.077929190
2      -0.091259116        -0.07658792      -0.01788633        0.075836845
3      21.154690859        19.48411330      -0.09210118       -0.077929190
4      -0.032063997        -0.07622736      -0.07303704       -0.021837578
5      -0.096563668        -0.07982437      -0.07785388       -0.003232343
6      -0.023587807        -0.09317109       0.03255298       -0.073075681
7      -0.096563668        -0.09850422      -0.09210118       -0.077929190
8      -0.096563668        -0.09850422      21.75815448       19.969765915
9      -0.078333256        -0.07944753      -0.05345205       -0.076700602
10     -0.003564406        -0.07561406      -0.05742290       -0.032360494
11     -0.034040828        -0.09850422      -0.09210118       -0.077929190
12      2.997247471         6.49391648      -0.09210118       -0.077929190
13      0.332417986        -0.09850422      -0.09210118       -0.077929190
14     -0.096563668        -0.09850422       0.11701102        0.196158329
15     -0.096563668        -0.09850422      -0.09210118       -0.077929190
   ageing_score mean_hl_hours    mean_mt       ratio
1   -0.10466169    0.13252335 -1.2972336  0.15241154
2   -0.20503093    0.12181446 -1.2171704 -0.59063611
3   -0.36026256   -0.16121042  0.6684024  1.04445364
4    4.62607404   -0.03548911 -0.2593467 -0.28429824
5   -0.09331444    1.31396101 -1.0835775  0.29894576
6   -0.18630797   -0.22178718 -1.1887484  1.31735243
7   -0.32344219   -0.55457759  0.4250499  2.00394766
8   -0.30030082   -0.30720517  0.6432077  3.03966776
9   -0.14942466    0.01311493  0.6554852 -0.55837202
10  -0.14137912   -0.30285948  0.7128714  1.29022333
11  -0.30557684   -0.21282117  0.3143284  0.94934903
12   0.88487444   -0.35382374 -0.5817761  0.30247869
13  -0.34002913   -0.00726506  0.6764472  0.00238155
14   0.34227884   11.83994168  0.5978710  1.75345408
15  -0.03661717   -0.47419382  0.5339174  1.78772006

Clustering vector:
1433B_HUMAN 1433E_HUMAN 1433F_HUMAN 1433G_HUMAN 1433Z_HUMAN  2AAA_HUMAN 
          2           9           2           2           9           9 
 2ABA_HUMAN 3HIDH_HUMAN  6PGL_HUMAN  AAAT_HUMAN  AATC_HUMAN ABHDA_HUMAN 
          2           9           2           9           9           9 
ACADM_HUMAN  ACBP_HUMAN ACL6A_HUMAN  ACLY_HUMAN  ACON_HUMAN ACTN1_HUMAN 
          2           2           9           9           2           5 
ACTN4_HUMAN   ADK_HUMAN  ADNP_HUMAN  AHNK_HUMAN AIMP1_HUMAN AL9A1_HUMAN 
          9           9          10          10           2           9 
ALDH2_HUMAN ALDOC_HUMAN  ALDR_HUMAN  AMPL_HUMAN AN32A_HUMAN AN32B_HUMAN 
          2           2           2           9          10          10 
AN32E_HUMAN  ANM5_HUMAN ANXA5_HUMAN AP3B1_HUMAN   AQR_HUMAN ARFP1_HUMAN 
          6           9           9           9           9           9 
ARI1A_HUMAN  ARP2_HUMAN  ARP3_HUMAN  ASNS_HUMAN ATX10_HUMAN  B2MG_HUMAN 
         10           1           2           9           2           9 
 BASI_HUMAN BASP1_HUMAN BAZ1B_HUMAN BOLA2_HUMAN  BRD4_HUMAN  BYST_HUMAN 
          2           6          10           2          10          10 
 BZW1_HUMAN  C1TC_HUMAN C2D1A_HUMAN  CALR_HUMAN CAND1_HUMAN CAPR1_HUMAN 
          9           9           6           6           9           6 
 CATA_HUMAN  CATD_HUMAN CAZA1_HUMAN  CBR1_HUMAN  CBX3_HUMAN  CBX5_HUMAN 
          9           2           2           2           6           6 
CCAR1_HUMAN CCAR2_HUMAN CD2AP_HUMAN CDC42_HUMAN CDC5L_HUMAN CDC73_HUMAN 
          6          12           6           9          10           9 
CDK12_HUMAN  CH10_HUMAN  CH60_HUMAN CHRD1_HUMAN CHTOP_HUMAN CKAP4_HUMAN 
         10           9           9           2          10          10 
CKAP5_HUMAN  CLH1_HUMAN CLIC1_HUMAN CLIP1_HUMAN  CLPX_HUMAN   CLU_HUMAN 
          9           2           9          10           9           9 
 CNBP_HUMAN  COPB_HUMAN  COPD_HUMAN COPG1_HUMAN COTL1_HUMAN CPIN1_HUMAN 
          9           2           9           2           9           9 
CPSF1_HUMAN CPSF2_HUMAN CPSF5_HUMAN CPSF7_HUMAN  CSN6_HUMAN CSTF2_HUMAN 
          2           9           2           6           2           6 
CSTF3_HUMAN  CTR9_HUMAN  CUL1_HUMAN  CUL3_HUMAN CUL4A_HUMAN CWC15_HUMAN 
         11          10           9           9           9          13 
 CYBP_HUMAN DAZP1_HUMAN   DCK_HUMAN  DDB1_HUMAN DDX21_HUMAN DDX42_HUMAN 
          9           6           9           9          10           6 
DDX46_HUMAN   DEK_HUMAN  DHE3_HUMAN DHX15_HUMAN DHX36_HUMAN  DHX9_HUMAN 
          6           6           9           9           9           9 
DIDO1_HUMAN  DKC1_HUMAN  DLDH_HUMAN DNJA1_HUMAN DNJA2_HUMAN DNJB1_HUMAN 
         10           9           9           9          12          12 
DNLI3_HUMAN DNMT1_HUMAN  DRG1_HUMAN  DRG2_HUMAN DSRAD_HUMAN DX39B_HUMAN 
          9           9           9           2           6           2 
 ECH1_HUMAN  ECHA_HUMAN  ECHM_HUMAN  EDC4_HUMAN  EDF1_HUMAN  EEA1_HUMAN 
          9           9           2          11           6          10 
 EF1B_HUMAN  EF1G_HUMAN   EF2_HUMAN  EFGM_HUMAN  EFTU_HUMAN EIF3A_HUMAN 
          2           2           9           9           2          10 
EIF3E_HUMAN EIF3I_HUMAN EIF3J_HUMAN EIF3M_HUMAN  ELF1_HUMAN  ENOA_HUMAN 
          9           9           6           2          11           2 
 ENPL_HUMAN ERAP1_HUMAN ERCC3_HUMAN   ERH_HUMAN ERP29_HUMAN  ESTD_HUMAN 
          2           9           9          13           2           9 
 ETFA_HUMAN  ETFB_HUMAN  EZRI_HUMAN F10A1_HUMAN F136A_HUMAN FABP5_HUMAN 
          2           9           6           6           2           9 
 FAF1_HUMAN   FAS_HUMAN  FEN1_HUMAN FKBP3_HUMAN FKBP4_HUMAN FKBP8_HUMAN 
          9           9           4           9           9          10 
 FLNA_HUMAN  FLNB_HUMAN  FPPS_HUMAN FUBP1_HUMAN FUBP2_HUMAN G3BP1_HUMAN 
          9           9           2           6          10           6 
G3BP2_HUMAN   G3P_HUMAN  G6PD_HUMAN  G6PI_HUMAN GANAB_HUMAN GFPT1_HUMAN 
         10           2           9           2           2           2 
 GLYM_HUMAN GOGB1_HUMAN GRP75_HUMAN GRPE1_HUMAN  GSHR_HUMAN GSLG1_HUMAN 
          9          10           2           2           9           9 
GSTO1_HUMAN GSTP1_HUMAN GT251_HUMAN  HCD2_HUMAN HDDC2_HUMAN HEAT1_HUMAN 
          2           2           9           9           9           9 
 HEM6_HUMAN HNRH3_HUMAN HNRL1_HUMAN HNRL2_HUMAN HNRPF_HUMAN HNRPL_HUMAN 
          9           9          10           6           2          10 
HNRPM_HUMAN HNRPQ_HUMAN HNRPR_HUMAN HNRPU_HUMAN HS105_HUMAN HS90A_HUMAN 
         10           6           6           1           9           4 
HS90B_HUMAN HSP74_HUMAN HSP7C_HUMAN  HXK2_HUMAN HYOU1_HUMAN I2BP2_HUMAN 
          4           2           4           9           2           6 
IDH3A_HUMAN  IDI1_HUMAN  IF2A_HUMAN  IF2B_HUMAN  IF2G_HUMAN  IF2P_HUMAN 
          2           9           9          10           9          10 
IF4A3_HUMAN IF4G1_HUMAN   IF5_HUMAN   IF6_HUMAN  ILEU_HUMAN  ILF3_HUMAN 
          9          10           2           9           2           6 
 IMA1_HUMAN  IMA5_HUMAN  IMB1_HUMAN  IPO7_HUMAN  IPYR_HUMAN IQGA1_HUMAN 
          9           9           9           9           9           9 
 ITB1_HUMAN   IVD_HUMAN  IWS1_HUMAN  JUND_HUMAN  KAD2_HUMAN  KAD3_HUMAN 
          9           9          10           6           9           2 
KHDR1_HUMAN  KINH_HUMAN  KPYM_HUMAN  KTHY_HUMAN  KYNU_HUMAN LAP2A_HUMAN 
          6          10           9           9           9          11 
LARP1_HUMAN LASP1_HUMAN    LA_HUMAN   LBR_HUMAN  LDHA_HUMAN  LDHB_HUMAN 
         10          10           9           2           9           9 
 LEG1_HUMAN LETM1_HUMAN  LGUL_HUMAN  LIS1_HUMAN LKHA4_HUMAN  LMNA_HUMAN 
          2           9           9           9           9          10 
LMNB1_HUMAN  LONM_HUMAN LPPRC_HUMAN LRC47_HUMAN LRC59_HUMAN LS14A_HUMAN 
         14           9           2           2           6          11 
 LSM6_HUMAN  LSM8_HUMAN  LYAR_HUMAN  MANF_HUMAN  MAOM_HUMAN  MAP2_HUMAN 
          9          13           3           9           2           6 
 MAP4_HUMAN MARCS_HUMAN MAT2B_HUMAN MATR3_HUMAN  MCES_HUMAN  MCM2_HUMAN 
         10          10           9          10          10           2 
 MCM4_HUMAN  MCM5_HUMAN  MCM6_HUMAN MCMBP_HUMAN  MDC1_HUMAN  MDHC_HUMAN 
          9           9           9           2           6           9 
 MDHM_HUMAN  MDN1_HUMAN MECP2_HUMAN METK2_HUMAN   MIF_HUMAN  MK01_HUMAN 
          9           9          14           9           9           4 
 MOES_HUMAN  MPPB_HUMAN  MPRD_HUMAN  MSH6_HUMAN  MTA2_HUMAN  MYH9_HUMAN 
         10           9           9           9           2           6 
MYPT1_HUMAN NAA15_HUMAN NDUS1_HUMAN NDUS3_HUMAN  NEB2_HUMAN NEDD8_HUMAN 
         10           9           2           9          15           2 
NIPS1_HUMAN  NIT2_HUMAN  NMT1_HUMAN NOLC1_HUMAN  NONO_HUMAN NP1L4_HUMAN 
          9           2           9           6           5           6 
  NPM_HUMAN   NSF_HUMAN NU133_HUMAN NU153_HUMAN NUCB1_HUMAN  NUCL_HUMAN 
          4           9           9          10          10           6 
NUP50_HUMAN NUP88_HUMAN  ODO2_HUMAN  ODP2_HUMAN  ODPA_HUMAN  ODPB_HUMAN 
          6           9           9           9           9           9 
 P5CS_HUMAN  P66A_HUMAN  P66B_HUMAN PA2G4_HUMAN PABP1_HUMAN PAIRB_HUMAN 
          2          10           6           2           6           6 
PARK7_HUMAN PARP1_HUMAN PCKGM_HUMAN  PCNA_HUMAN PDC6I_HUMAN PDCD4_HUMAN 
          4           4           2           4           9           9 
PDCD5_HUMAN PDCD6_HUMAN PDIA1_HUMAN PDIA3_HUMAN PDIA4_HUMAN PDIA6_HUMAN 
          6           9           9           2           2           2 
PDLI1_HUMAN PDS5B_HUMAN PEBP1_HUMAN PELP1_HUMAN  PFD2_HUMAN  PFD3_HUMAN 
         10           9           9           6           6           2 
 PFD5_HUMAN PGAM1_HUMAN  PGK1_HUMAN  PGM1_HUMAN  PGM2_HUMAN PGRC2_HUMAN 
          9           9           2           9           9           2 
 PIMT_HUMAN PITH1_HUMAN  PLEC_HUMAN PLPL6_HUMAN PLRG1_HUMAN  PNPH_HUMAN 
          2           9           2           9          10           9 
PNPT1_HUMAN  PP1A_HUMAN PP1RA_HUMAN  PPCE_HUMAN  PPIA_HUMAN  PPIB_HUMAN 
          2           9          10           9           2           2 
 PPIH_HUMAN PRDX1_HUMAN PRDX2_HUMAN PRDX3_HUMAN PRDX5_HUMAN PRDX6_HUMAN 
          9           2           9           2           2           9 
PRKDC_HUMAN PROF1_HUMAN PRP19_HUMAN  PRP4_HUMAN  PRP6_HUMAN  PRP8_HUMAN 
          4           2           2           2          10           2 
 PRS4_HUMAN PRS6B_HUMAN  PRS7_HUMAN  PRS8_HUMAN  PSA1_HUMAN  PSA2_HUMAN 
          9           9           9           9           9           9 
 PSA3_HUMAN  PSA5_HUMAN  PSA7_HUMAN   PSA_HUMAN  PSB1_HUMAN PSD11_HUMAN 
          9           9           9           9           9           9 
PSD12_HUMAN PSMD1_HUMAN PSMD2_HUMAN PSMD3_HUMAN PSMD5_HUMAN PSME1_HUMAN 
          9           9           9           9           2           2 
PSME3_HUMAN PTBP1_HUMAN PUF60_HUMAN  PUR6_HUMAN  PUR9_HUMAN  PURA_HUMAN 
          9           2           2           9           2          10 
 PUS7_HUMAN  QCR7_HUMAN   QKI_HUMAN   QOR_HUMAN RAB14_HUMAN RAB5C_HUMAN 
          9           9           2           9           9           2 
RAD21_HUMAN  RADI_HUMAN RAE1L_HUMAN RAGP1_HUMAN RBBP4_HUMAN RBM12_HUMAN 
         10           6           9           9           9          10 
RBM26_HUMAN RBM8A_HUMAN  RCC2_HUMAN RD23A_HUMAN RD23B_HUMAN RECQ1_HUMAN 
         10           6           9          10          10           2 
RENT1_HUMAN REPS1_HUMAN  RFA1_HUMAN  RFA2_HUMAN  RL10_HUMAN  RL12_HUMAN 
         12           6           4           4           9           9 
 RL14_HUMAN RL23A_HUMAN RL27A_HUMAN  RL27_HUMAN  RL30_HUMAN   RL3_HUMAN 
          6          10           9           9           9           9 
  RL4_HUMAN   RL5_HUMAN   RL7_HUMAN  RM12_HUMAN  RM49_HUMAN  ROA2_HUMAN 
          9           9           9           2           9           6 
 RPA1_HUMAN  RPA2_HUMAN  RPB2_HUMAN  RPN1_HUMAN RRP44_HUMAN  RS12_HUMAN 
          9           9           9           9           2           2 
 RS13_HUMAN  RS20_HUMAN  RS28_HUMAN   RS3_HUMAN   RS6_HUMAN   RS8_HUMAN 
          9           9           2           4          10           9 
  RS9_HUMAN  RSF1_HUMAN  RSU1_HUMAN  RT29_HUMAN  RTCB_HUMAN  RU17_HUMAN 
          9           7           9           9           9          10 
 RU2B_HUMAN S10A6_HUMAN SAFB1_HUMAN SAFB2_HUMAN  SAHH_HUMAN   SAP_HUMAN 
          9           9          10          10           9           9 
 SBDS_HUMAN SCOT1_HUMAN  SERC_HUMAN   SET_HUMAN  SF01_HUMAN SF3A1_HUMAN 
          9           2           9          10           6          10 
SF3A3_HUMAN SF3B1_HUMAN SF3B2_HUMAN SF3B3_HUMAN SF3B5_HUMAN SF3B6_HUMAN 
          2          10           6           9          13           9 
 SFPQ_HUMAN  SGT1_HUMAN SIN3A_HUMAN  SKP1_HUMAN SLIRP_HUMAN SMC1A_HUMAN 
          6           9           4          10           2          10 
 SMC3_HUMAN SMCA4_HUMAN SMCA5_HUMAN SMCE1_HUMAN  SMD1_HUMAN  SMD2_HUMAN 
          6          10           9           6           9          10 
SMRC1_HUMAN  SND1_HUMAN SNR40_HUMAN SNUT1_HUMAN  SNX3_HUMAN  SNX6_HUMAN 
          6           2           9          10           9           9 
 SODC_HUMAN SP16H_HUMAN  SPB6_HUMAN  SPSY_HUMAN SPT5H_HUMAN SPTB2_HUMAN 
          4           9           9           2          10           2 
SPTN1_HUMAN SR140_HUMAN SRP14_HUMAN SRPK1_HUMAN  SRRT_HUMAN SRS11_HUMAN 
          2           6           9          10           6          10 
SRSF6_HUMAN SRSF7_HUMAN SSRP1_HUMAN STAG2_HUMAN STAT1_HUMAN STIP1_HUMAN 
         10           6          10           9           4           2 
STRAP_HUMAN SUCB1_HUMAN SUCB2_HUMAN SUMO2_HUMAN  SYAM_HUMAN  SYDM_HUMAN 
          2           2           2          10           2           9 
 SYFB_HUMAN  SYIM_HUMAN  SYLM_HUMAN SYMPK_HUMAN  T2EB_HUMAN TAGL2_HUMAN 
          9           9           9          11           6           2 
TCEA1_HUMAN  TCOF_HUMAN  TCP4_HUMAN  TCPA_HUMAN  TCPD_HUMAN  TCPE_HUMAN 
         10           6          10           9           9           2 
 TCPH_HUMAN  TCPZ_HUMAN TCRG1_HUMAN  TCTP_HUMAN  TERA_HUMAN TFCP2_HUMAN 
          9           9           6           2           4           9 
 TFR1_HUMAN  THIC_HUMAN  THIL_HUMAN  THIM_HUMAN THOC1_HUMAN THOC2_HUMAN 
          9           2           2           9           9           9 
THOC6_HUMAN TIF1B_HUMAN   TKT_HUMAN  TLN1_HUMAN TMOD3_HUMAN TNPO1_HUMAN 
          9           6           9           9           9           2 
 TOP1_HUMAN TPD54_HUMAN  TPIS_HUMAN  TPM4_HUMAN   TPR_HUMAN TR150_HUMAN 
          9          10           9           6          10          11 
TRIM4_HUMAN TRIPC_HUMAN TXLNA_HUMAN TXND5_HUMAN  TYPH_HUMAN  TYY1_HUMAN 
          9          11          10           9           9          10 
U2AF2_HUMAN U3IP2_HUMAN  U520_HUMAN  U5S1_HUMAN UB2L3_HUMAN  UBA1_HUMAN 
          6           9           9           9           9           2 
 UBA6_HUMAN  UBR5_HUMAN UBXN1_HUMAN  UFC1_HUMAN  UGPA_HUMAN  VASP_HUMAN 
          9          10           6           9           9          10 
VATB2_HUMAN VATC1_HUMAN VIGLN_HUMAN  VIME_HUMAN  VINC_HUMAN VPS35_HUMAN 
          9           9           9           5           9           9 
VPS4B_HUMAN  VTA1_HUMAN  WDR1_HUMAN WDR26_HUMAN  WDR5_HUMAN WIPF1_HUMAN 
          9           6           9           9           9           8 
 XPO1_HUMAN  XPO7_HUMAN  XPOT_HUMAN XRCC5_HUMAN XRCC6_HUMAN  XRN2_HUMAN 
          9           2           9           4           4           9 
ZC3H4_HUMAN ZC3HF_HUMAN ZCHC8_HUMAN   ZFR_HUMAN ZMAT2_HUMAN ZN638_HUMAN 
         10           6          10          10          10          10 
 ZPR1_HUMAN 
          6 

Within cluster sum of squares by cluster:
 [1]  80.62915 356.02936   0.00000 100.77385  83.72987 151.55113   0.00000
 [8]   0.00000 400.08578 237.02206 314.58719  55.10602 188.65998  12.20153
[15]   0.00000
 (between_SS / total_SS =  80.7 %)

Available components:

[1] "cluster"      "centers"      "totss"        "withinss"     "tot.withinss"
[6] "betweenss"    "size"         "iter"         "ifault"      

Evaluation of results:

             Length Class  Mode   
cluster      571    -none- numeric
centers      270    -none- numeric
totss          1    -none- numeric
withinss      15    -none- numeric
tot.withinss   1    -none- numeric
betweenss      1    -none- numeric
size          15    -none- numeric
iter           1    -none- numeric
ifault         1    -none- numeric

Getting the cluster members:

Heatmap to see the patterns:

Stability metrics and ageing

Disorder metrics

Joining everything:

K-means clustering with 10 clusters of sizes 56, 71, 75, 56, 2, 35, 51, 136, 25, 75

Cluster means:
   mean_hl_hours    mean_mt      ratio
1     -0.4351049  0.6709120  1.9559220
2     -0.2485475 -0.6592530 -0.4032486
3     -0.3955260  0.7046951  0.3896776
4     -0.2761747 -1.7485734 -0.3688449
5      9.7407126  0.5954430  1.7356894
6      1.2970572 -1.2031424 -0.5902620
7     -0.2129423 -1.2543257  1.5095866
8     -0.4984478  0.7184165 -0.6623440
9      2.2130486  0.6634842 -0.6235982
10     0.6078305  0.5986910 -0.5813849

Clustering vector:
1433B_HUMAN 1433E_HUMAN 1433F_HUMAN 1433G_HUMAN 1433Z_HUMAN  2AAA_HUMAN 
          2          10           2           4          10           8 
 2ABA_HUMAN 3HIDH_HUMAN  6PGL_HUMAN  AAAT_HUMAN  AATC_HUMAN ABHDA_HUMAN 
          4          10           6           8           8           9 
ACADM_HUMAN  ACBP_HUMAN ACL6A_HUMAN  ACLY_HUMAN  ACON_HUMAN  ACTB_HUMAN 
          4           6           8           8           2           4 
ACTN1_HUMAN ACTN4_HUMAN   ADK_HUMAN  ADNP_HUMAN  AHNK_HUMAN AIMP1_HUMAN 
          9          10          10           3           1           4 
AKA12_HUMAN AL9A1_HUMAN ALDH2_HUMAN ALDOC_HUMAN  ALDR_HUMAN  AMPL_HUMAN 
          1           9           2           6           6          10 
AN32A_HUMAN AN32B_HUMAN AN32E_HUMAN  ANM5_HUMAN ANXA5_HUMAN AP3B1_HUMAN 
         10          10           6           8          10           3 
  AQR_HUMAN ARFP1_HUMAN ARI1A_HUMAN  ARP2_HUMAN  ARP3_HUMAN ASAH1_HUMAN 
          8           3           1           2           6          10 
 ASNS_HUMAN AT1B3_HUMAN ATX10_HUMAN  BASI_HUMAN BASP1_HUMAN BAZ1B_HUMAN 
          8           8           2           4           7           3 
  BIP_HUMAN BOLA2_HUMAN  BRD4_HUMAN  BROX_HUMAN  BYST_HUMAN  BZW1_HUMAN 
          2           4           1           4           3           8 
 C1TC_HUMAN C2D1A_HUMAN  CALR_HUMAN  CALU_HUMAN CAND1_HUMAN CAPR1_HUMAN 
         10           7           7           2          10           7 
 CATA_HUMAN  CATC_HUMAN  CATD_HUMAN CAZA1_HUMAN  CBR1_HUMAN  CBX3_HUMAN 
         10           9           2           6           4           7 
 CBX5_HUMAN CCAR1_HUMAN CCAR2_HUMAN CCD12_HUMAN CD2AP_HUMAN CDC42_HUMAN 
          7           7           3           1           7           2 
CDC5L_HUMAN CDK12_HUMAN  CH10_HUMAN  CH60_HUMAN CHRD1_HUMAN CHTOP_HUMAN 
          1           1           8           9           2           1 
CKAP4_HUMAN CKAP5_HUMAN  CLH1_HUMAN CLIC1_HUMAN CLIP1_HUMAN  CLPX_HUMAN 
         10           3           2          10           1           8 
  CLU_HUMAN  CNBP_HUMAN  COPB_HUMAN  COPD_HUMAN COPG1_HUMAN COTL1_HUMAN 
          8           8           4           3           2           9 
CPIN1_HUMAN CPSF1_HUMAN CPSF2_HUMAN CPSF5_HUMAN CPSF7_HUMAN CSK21_HUMAN 
          8           2           8           2           7           2 
 CSN6_HUMAN CSTF2_HUMAN CSTF3_HUMAN  CTR9_HUMAN  CUL1_HUMAN  CUL3_HUMAN 
          2           7           8           3           8           8 
CUL4A_HUMAN CWC15_HUMAN  CYBP_HUMAN DAZP1_HUMAN   DCK_HUMAN  DDB1_HUMAN 
          8           1           8           7           8           8 
DDX21_HUMAN DDX42_HUMAN DDX46_HUMAN   DEK_HUMAN  DHE3_HUMAN DHX15_HUMAN 
          3           7           4           7           9           2 
DHX36_HUMAN  DHX9_HUMAN DIDO1_HUMAN  DKC1_HUMAN  DLDH_HUMAN DNJA2_HUMAN 
          8          10           1          10          10           2 
DNJB1_HUMAN DNJC1_HUMAN DNLI3_HUMAN DNMT1_HUMAN  DRG1_HUMAN  DRG2_HUMAN 
          4           3           8           3           8           4 
DSRAD_HUMAN DX39B_HUMAN  ECH1_HUMAN  ECHA_HUMAN  ECHM_HUMAN  EDC4_HUMAN 
          4           9          10          10           6           3 
 EDF1_HUMAN  EEA1_HUMAN  EF1B_HUMAN  EF1G_HUMAN   EF2_HUMAN  EFGM_HUMAN 
          7           3           4           2           8           8 
 EFTU_HUMAN EIF3A_HUMAN EIF3E_HUMAN EIF3I_HUMAN EIF3J_HUMAN EIF3M_HUMAN 
          6           3           8           8           7           4 
  ELL_HUMAN  ENOA_HUMAN  ENPL_HUMAN ERAP1_HUMAN ERCC3_HUMAN   ERH_HUMAN 
          7           6           4           8           8           8 
ERP29_HUMAN  ESTD_HUMAN  ETFA_HUMAN  ETFB_HUMAN  EZRI_HUMAN F10A1_HUMAN 
          6           8           6          10           7           7 
F136A_HUMAN FABP5_HUMAN  FAF1_HUMAN FAH2A_HUMAN   FAS_HUMAN  FEN1_HUMAN 
          4           8           3          10           8           4 
 FIP1_HUMAN FKBP3_HUMAN FKBP4_HUMAN FKBP8_HUMAN  FLNA_HUMAN  FLNB_HUMAN 
          1           3           8           3           3          10 
 FPPS_HUMAN FUBP1_HUMAN FUBP2_HUMAN G3BP1_HUMAN G3BP2_HUMAN   G3P_HUMAN 
          2           7           1           7           1           6 
 G6PD_HUMAN  G6PI_HUMAN GANAB_HUMAN GFPT1_HUMAN  GLYM_HUMAN GOGB1_HUMAN 
         10           6           4           4           8           3 
GRP75_HUMAN GRPE1_HUMAN  GSHR_HUMAN GSLG1_HUMAN GSTO1_HUMAN GSTP1_HUMAN 
          2           4          10           8           6           4 
GT251_HUMAN  HCD2_HUMAN HDDC2_HUMAN HEAT1_HUMAN  HEM6_HUMAN HNRH3_HUMAN 
          8           9          10           8           8           8 
HNRL1_HUMAN HNRL2_HUMAN HNRPF_HUMAN HNRPL_HUMAN HNRPM_HUMAN HNRPQ_HUMAN 
          1           7           4           3           3           2 
HNRPR_HUMAN HNRPU_HUMAN HS105_HUMAN HS90A_HUMAN HS90B_HUMAN HSP74_HUMAN 
          7           7           3           3           2           4 
HSP7C_HUMAN  HXK2_HUMAN HYOU1_HUMAN IDH3A_HUMAN  IDI1_HUMAN  IF2A_HUMAN 
          2           8           4           6           8           8 
 IF2B_HUMAN  IF2G_HUMAN  IF2P_HUMAN IF4A3_HUMAN IF4G1_HUMAN   IF5_HUMAN 
          3           8           1           8           1           2 
  IF6_HUMAN  ILEU_HUMAN  ILF3_HUMAN  IMA4_HUMAN  IMA5_HUMAN  IMB1_HUMAN 
          8           6           7           8           8           8 
 IPO7_HUMAN  IPYR_HUMAN IQGA1_HUMAN  ITB1_HUMAN   IVD_HUMAN  IWS1_HUMAN 
          8           2           8           8          10           1 
 JUND_HUMAN  KAD2_HUMAN  KAD3_HUMAN KHDR1_HUMAN  KINH_HUMAN  KPYM_HUMAN 
          7           9           6           7           3          10 
 KTHY_HUMAN  KYNU_HUMAN LACB2_HUMAN LAP2A_HUMAN LARP1_HUMAN LASP1_HUMAN 
          8           8           8           6           1           1 
   LA_HUMAN   LBR_HUMAN  LDHA_HUMAN  LDHB_HUMAN  LEG1_HUMAN LETM1_HUMAN 
         10           6          10          10           6           3 
 LGUL_HUMAN  LIS1_HUMAN LKHA4_HUMAN  LMNA_HUMAN LMNB1_HUMAN  LONM_HUMAN 
          8           8          10           3           5          10 
LPPRC_HUMAN LRC47_HUMAN LRC59_HUMAN LS14A_HUMAN  LSM6_HUMAN  LSM8_HUMAN 
          4           2           4           1           8          10 
LUZP1_HUMAN  LYAR_HUMAN LYPA1_HUMAN  MANF_HUMAN  MAOM_HUMAN  MAP2_HUMAN 
          1           3           8           8           2           2 
 MAP4_HUMAN MARCS_HUMAN MAT2B_HUMAN MATR3_HUMAN  MCES_HUMAN  MCM2_HUMAN 
          1           1           8           1           3           4 
 MCM4_HUMAN  MCM5_HUMAN  MCM6_HUMAN MCMBP_HUMAN  MDC1_HUMAN  MDHC_HUMAN 
          8           8           8           4           1           9 
 MDHM_HUMAN  MDN1_HUMAN MECP2_HUMAN METK2_HUMAN   MIF_HUMAN  MK01_HUMAN 
          9           8           5           8           8           2 
 MK14_HUMAN  MOES_HUMAN  MPPB_HUMAN  MPRD_HUMAN  MSH6_HUMAN  MYH9_HUMAN 
          8           3           8           8           8           7 
MYPT1_HUMAN NAA15_HUMAN NDUS1_HUMAN NDUS3_HUMAN  NEB2_HUMAN NEDD8_HUMAN 
          1           8           2           2           1           4 
NIPS1_HUMAN  NIT2_HUMAN  NMT1_HUMAN NOLC1_HUMAN  NONO_HUMAN NP1L4_HUMAN 
         10           2           3           7           7           2 
  NPM_HUMAN   NSF_HUMAN NU133_HUMAN NUCB1_HUMAN  NUCL_HUMAN NUP50_HUMAN 
          7           8           8           1           7           7 
NUP88_HUMAN  ODO2_HUMAN  ODP2_HUMAN  ODPA_HUMAN  ODPB_HUMAN P4HA1_HUMAN 
          8           9          10           8          10           4 
 P5CS_HUMAN  P66A_HUMAN PA2G4_HUMAN PABP1_HUMAN PAIRB_HUMAN PARK7_HUMAN 
          4           1           4           4           7          10 
PARP1_HUMAN PCKGM_HUMAN  PCNA_HUMAN PDC6I_HUMAN PDCD5_HUMAN PDCD6_HUMAN 
          2           4           2           3           7           8 
PDIA1_HUMAN PDIA3_HUMAN PDIA4_HUMAN PDIA6_HUMAN PDLI1_HUMAN PDS5B_HUMAN 
         10           4           2           2           3           3 
PEBP1_HUMAN PELP1_HUMAN  PFD2_HUMAN  PFD4_HUMAN PGAM1_HUMAN  PGK1_HUMAN 
         10           7           2           6          10           6 
 PGM1_HUMAN  PGM2_HUMAN PGRC2_HUMAN  PIMT_HUMAN PITH1_HUMAN PLBL2_HUMAN 
          9           9           4           4           3           8 
 PLEC_HUMAN PLOD1_HUMAN PLPL6_HUMAN PLRG1_HUMAN  PNPH_HUMAN PNPT1_HUMAN 
          2           8           8           3          10           2 
 PP1A_HUMAN PP1RA_HUMAN  PPCE_HUMAN  PPIA_HUMAN  PPIB_HUMAN  PPIH_HUMAN 
          8           1          10           6           2           8 
PRDX1_HUMAN PRDX2_HUMAN PRDX3_HUMAN PRDX5_HUMAN PRDX6_HUMAN PRKDC_HUMAN 
          4           9           6           6          10           9 
PROF1_HUMAN PRP19_HUMAN  PRP4_HUMAN  PRP6_HUMAN  PRP8_HUMAN  PRS4_HUMAN 
          6           2           4           3           2           3 
PRS6B_HUMAN  PRS7_HUMAN  PRS8_HUMAN  PSA1_HUMAN  PSA2_HUMAN  PSA3_HUMAN 
          8           8           8          10          10          10 
 PSA5_HUMAN  PSA7_HUMAN   PSA_HUMAN  PSB1_HUMAN PSD11_HUMAN PSD12_HUMAN 
         10          10          10          10           8           8 
PSMD1_HUMAN PSMD2_HUMAN PSMD3_HUMAN PSMD5_HUMAN PSME1_HUMAN PSME3_HUMAN 
          8           2           3           2           2           8 
PTBP1_HUMAN PUF60_HUMAN  PUR6_HUMAN  PUR9_HUMAN  PURA_HUMAN  PUS7_HUMAN 
          4           2          10           2           3           8 
  PYC_HUMAN  QCR7_HUMAN   QOR_HUMAN RAB14_HUMAN RAB5C_HUMAN  RAC1_HUMAN 
          8           9           8           8           2           8 
 RADI_HUMAN RAE1L_HUMAN RAGP1_HUMAN RBM12_HUMAN RBM26_HUMAN RBM8A_HUMAN 
          7           8           2           1           1           7 
 RCC2_HUMAN RD23A_HUMAN RD23B_HUMAN RECQ1_HUMAN RENT1_HUMAN REPS1_HUMAN 
          3           1           1           4           4           1 
 RFA1_HUMAN  RFA2_HUMAN  RL10_HUMAN  RL12_HUMAN  RL14_HUMAN RL23A_HUMAN 
          8           3           8           2           4           3 
RL27A_HUMAN  RL27_HUMAN  RL30_HUMAN   RL3_HUMAN   RL4_HUMAN   RL5_HUMAN 
         10          10           8          10          10           8 
  RL7_HUMAN  RM12_HUMAN  RM49_HUMAN  ROA2_HUMAN  RPA1_HUMAN  RPA2_HUMAN 
         10           6           3           7           8           8 
 RPB2_HUMAN  RPN1_HUMAN RRP44_HUMAN  RS12_HUMAN  RS13_HUMAN  RS20_HUMAN 
          8           8           2           2           8          10 
 RS28_HUMAN   RS3_HUMAN   RS6_HUMAN   RS8_HUMAN   RS9_HUMAN  RSF1_HUMAN 
          4          10           3          10          10           1 
 RSU1_HUMAN  RT29_HUMAN  RTCB_HUMAN  RU17_HUMAN  RU2B_HUMAN S10A6_HUMAN 
          8           8           8           1           3          10 
SAFB1_HUMAN SAFB2_HUMAN  SAHH_HUMAN   SAP_HUMAN  SBDS_HUMAN SCOT1_HUMAN 
          1           1          10           8           8           6 
 SERC_HUMAN SERPH_HUMAN   SET_HUMAN  SF01_HUMAN SF3A1_HUMAN SF3A3_HUMAN 
          8           2           1           7           1           4 
SF3B1_HUMAN SF3B2_HUMAN SF3B3_HUMAN SF3B5_HUMAN  SFPQ_HUMAN  SGT1_HUMAN 
          3           7          10           8           7           8 
SIN3A_HUMAN SLIRP_HUMAN SMC1A_HUMAN  SMC3_HUMAN SMCA4_HUMAN SMCA5_HUMAN 
          3           4           3           2           1           3 
 SMD1_HUMAN  SMD2_HUMAN SMRC1_HUMAN  SND1_HUMAN SNR40_HUMAN SNUT1_HUMAN 
          3           9           7           4           8           1 
 SNX3_HUMAN  SNX6_HUMAN  SODC_HUMAN SP16H_HUMAN  SPB6_HUMAN  SPSY_HUMAN 
          8           8           6           3           9           2 
SPT5H_HUMAN SPTB2_HUMAN SPTN1_HUMAN SR140_HUMAN SRP14_HUMAN SRPK1_HUMAN 
          3           2           4           7           3           3 
 SRRT_HUMAN SRS11_HUMAN SRSF6_HUMAN SRSF7_HUMAN SSRP1_HUMAN STAG2_HUMAN 
          7           1           1           7           3           3 
STAT1_HUMAN STIP1_HUMAN STRAP_HUMAN SUCB1_HUMAN SUCB2_HUMAN SUMO2_HUMAN 
          8           2           2           4           6           3 
 SYAM_HUMAN  SYDM_HUMAN  SYFB_HUMAN  SYIM_HUMAN  SYLM_HUMAN SYMPK_HUMAN 
          4           8          10          10           8           3 
 T2EB_HUMAN TAGL2_HUMAN TCEA1_HUMAN  TCOF_HUMAN  TCP4_HUMAN  TCPA_HUMAN 
          2           2           3           7           1          10 
 TCPD_HUMAN  TCPE_HUMAN  TCPH_HUMAN  TCPZ_HUMAN TCRG1_HUMAN  TCTP_HUMAN 
         10           4          10          10           7           2 
 TERA_HUMAN TFCP2_HUMAN  TFR1_HUMAN  TGO1_HUMAN  THIC_HUMAN  THIL_HUMAN 
          8           3           8           7           2           6 
 THIM_HUMAN THOC1_HUMAN THOC2_HUMAN THOC6_HUMAN TIF1B_HUMAN   TKT_HUMAN 
          9           3           3           8           2           9 
 TLN1_HUMAN  TLS1_HUMAN TMOD3_HUMAN TNPO1_HUMAN  TOP1_HUMAN TPD54_HUMAN 
          2           1           3           2           3           3 
 TPIS_HUMAN  TPM4_HUMAN   TPR_HUMAN TR150_HUMAN TRIPC_HUMAN TXD12_HUMAN 
          9           6           1           1           3           2 
TXLNA_HUMAN TXND5_HUMAN  TYPH_HUMAN  TYY1_HUMAN U2AF2_HUMAN U3IP2_HUMAN 
          1          10           8           1           2           3 
 U520_HUMAN  U5S1_HUMAN UB2L3_HUMAN  UBA1_HUMAN  UBA6_HUMAN  UBR5_HUMAN 
          2           8           8           4          10           3 
UBXN1_HUMAN  UFC1_HUMAN  UGPA_HUMAN  VASP_HUMAN VATB2_HUMAN VATC1_HUMAN 
          7           8           9           1           8           8 
VIGLN_HUMAN  VIME_HUMAN  VINC_HUMAN VPS29_HUMAN VPS35_HUMAN VPS4B_HUMAN 
          8           6           9           8           8           3 
 VTA1_HUMAN  WDR1_HUMAN WDR26_HUMAN  WDR5_HUMAN WIPF1_HUMAN  XPO1_HUMAN 
          4          10           8          10           1           8 
 XPO7_HUMAN  XPOT_HUMAN XRCC5_HUMAN XRCC6_HUMAN  XRN2_HUMAN ZC3H4_HUMAN 
          4           8           6          10           3           1 
ZC3HF_HUMAN ZCHC8_HUMAN   ZFR_HUMAN ZMAT2_HUMAN ZN638_HUMAN  ZPR1_HUMAN 
          7           3           3           3           1           7 

Within cluster sum of squares by cluster:
 [1] 37.561272 30.494975 30.171854 26.638208  9.940778 28.442950 51.098721
 [8] 35.445359 18.904309 30.225477
 (between_SS / total_SS =  82.9 %)

Available components:

[1] "cluster"      "centers"      "totss"        "withinss"     "tot.withinss"
[6] "betweenss"    "size"         "iter"         "ifault"      

Evaluation of results:

             Length Class  Mode   
cluster      582    -none- numeric
centers       30    -none- numeric
totss          1    -none- numeric
withinss      10    -none- numeric
tot.withinss   1    -none- numeric
betweenss      1    -none- numeric
size          10    -none- numeric
iter           1    -none- numeric
ifault         1    -none- numeric

Getting the cluster members:

Heatmap to see the patterns:

PCA

Importance of components:
                          PC1    PC2    PC3
Standard deviation     1.0590 1.0116 0.9248
Proportion of Variance 0.3738 0.3411 0.2851
Cumulative Proportion  0.3738 0.7149 1.0000

                     PC1        PC2        PC3
mean_hl_hours -0.6773486  0.3667218 -0.6377413
mean_mt       -0.1316366 -0.9133215 -0.3853773
ratio          0.7237891  0.1770847 -0.6669110